Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379537 | 1.00 | TRPA1 (0.36) | TRPA1LMNAALOX15BLMPMP22 | |
| Acetone SCHEMBL293563 | 0.97 | TRPA1 (0.35) | TRPA1LMNAALOX15BLMPMP22 | |
| SCHEMBL2999479 | 0.82 | ALOX15 (0.39) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL373974 | 0.80 | TDP1 (0.43) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL373975 | 0.80 | TDP1 (0.43) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL10817873 | 0.78 | — | — | |
| SCHEMBL59412 | 0.78 | LMNA (0.39) | TRPA1LMNAALOX15BLMPMP22 | |
| SCHEMBL528542 | 0.78 | LMNA (0.39) | TRPA1LMNAALOX15BLMPMP22 | |
| SCHEMBL528543 | 0.78 | LMNA (0.39) | TRPA1LMNAALOX15BLMPMP22 | |
| SCHEMBL59410 | 0.78 | LMNA (0.39) | TRPA1LMNAALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084331-A2 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |