SCHEMBL2999479

SCHEMBL2999479

CC(=CCC(=O)O)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2D6 P10635 1/20 0.39
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32
NR1H3 Q13133 1/20 0.31
SLC15A2 Q16348 1/20 0.31
FFAR3 O14843 1/20 0.30
GLRA1 P23415 1/20 0.30
SLC6A9 P48067 1/20 0.30
OR51E2 Q9H255 1/20 0.30
TSHR P16473 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11024924 0.84 ALDH1A1 (0.47) ALOX15ALDH1A1CYP2D6LMNALDHA
SCHEMBL24358337 0.82 TRPA1 (0.36) ALOX15ALDH1A1LMNATDP1BLM
SCHEMBL20379537 0.82 TRPA1 (0.36) ALOX15ALDH1A1LMNATDP1BLM
Acetone SCHEMBL293563 0.80 TRPA1 (0.35) ALOX15ALDH1A1LMNATDP1BLM
SCHEMBL7138870 0.79 ALDH1A1 (0.43) ALOX15ALDH1A1CYP2D6LMNANR1H3
SCHEMBL275071 0.79 ALDH1A1 (0.43) ALOX15ALDH1A1CYP2D6LMNANR1H3
SCHEMBL2727259 0.79 ALDH1A1 (0.43) ALOX15ALDH1A1CYP2D6LMNANR1H3
SCHEMBL373974 0.78 TDP1 (0.43) ALOX15LMNATDP1BLMPMP22
SCHEMBL373975 0.78 TDP1 (0.43) ALOX15LMNATDP1BLMPMP22
SCHEMBL1622643 0.77 ALDH1A1 (0.41) ALOX15ALDH1A1CYP2D6LMNANR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119415-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2019-04-25 US claimed
EP-2152405-B2 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-04-05 EP claimed
CN-102112191-B Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2014-07-30 CN claimed
CN-101678318-B Graft copolymer for cation-exchange chromatography MERCK PATENT GMBH 2013-09-25 CN claimed
EP-2152405-B1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2012-10-17 EP claimed
CN-102112191-A Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2011-06-29 CN claimed
CN-101678318-A Graft copolymer for cation-exchange chromatography MERCK PATENT GMBH 2010-03-24 CN claimed
US-20190119415-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2019-04-25 US disclosed
EP-2152405-B2 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-04-05 EP disclosed
CN-102112191-B Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2014-07-30 CN disclosed
US-20140183136-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2014-07-03 US disclosed
CN-101678318-B Graft copolymer for cation-exchange chromatography MERCK PATENT GMBH 2013-09-25 CN disclosed
EP-2152405-B1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2012-10-17 EP disclosed
EP-2152405-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY Merck Patent GmbH (DE) 2010-02-17 EP disclosed
WO-2008145270-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2008-12-04 WO disclosed
EP-0503301-B1 Peptide derivatives and application thereof FUJI PHOTO FILM CO LTD (JP) 1997-11-26 EP disclosed
EP-0619118-B1 Use of peptide derivatives FUJI PHOTO FILM CO LTD (JP) 1997-06-11 EP disclosed
US-5436221-A Oligopeptides as antitumor agents FUJI PHOTO FILM CO., LTD. (JP) 1995-07-25 US disclosed
EP-0619118-A1 Use of peptide derivatives FUJI PHOTO FILM CO., LTD. (JP) 1994-10-12 EP disclosed
EP-0503301-A2 Peptide derivatives and application thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed