Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31312450 | 0.80 | PARP1 (0.62) | ARALDH1A1TDP1GFERHPGD | |
| SCHEMBL5332607 | 0.80 | PARP1 (0.62) | ARALDH1A1TDP1GFERHPGD | |
| SCHEMBL12298197 | 0.78 | MEN1 (0.51) | ARALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL5335867 | 0.74 | PARP1 (0.59) | ARALDH1A1TDP1GFERHPGD | |
| SCHEMBL31473178 | 0.74 | PARP1 (0.59) | ARALDH1A1TDP1GFERHPGD | |
| SCHEMBL29402764 | 0.74 | AR (0.69) | ARALDH1A1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL22501754 | 0.74 | AR (0.69) | ARALDH1A1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL3875172 | 0.73 | KIF11 (0.47) | ARALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL6325907 | 0.73 | CDK4 (0.69) | ARALDH1A1TDP1HPGDKDM4E | |
| SCHEMBL28407136 | 0.70 | AR (1.00) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | RXFP1, RXFP2, CX3CR1 | AR 1801/4885ALDH1A1 91/4885L3MBTL1 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.