Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.69 |
| ▸ | GLA | P06280 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22501754 | 1.00 | AR (0.69) | ARGLAKDM4EALDH1A1HPGD | |
| SCHEMBL1771660 | 0.87 | AR (0.71) | ARGLAKDM4EALDH1A1HPGD | |
| SCHEMBL28407136 | 0.82 | AR (1.00) | AR | |
| SCHEMBL74712 | 0.81 | AR (0.65) | ARGLAKDM4EALDH1A1HPGD | |
| SCHEMBL29379051 | 0.81 | AR (0.65) | ARGLAKDM4EALDH1A1HPGD | |
| SCHEMBL9014074 | 0.77 | S100B (0.47) | ARGLAKDM4EALDH1A1HPGD | |
| SCHEMBL9307979 | 0.75 | KDM4E (0.59) | GLAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL1378769 | 0.74 | TNKS2 (0.75) | ARGLAKDM4EALDH1A1HPGD | |
| SCHEMBL2435888 | 0.74 | AR (0.53) | ARGLAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6403688 | 0.74 | AR (0.50) | ARGLAALDH1A1HPGDIGLV6-57 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127050-A | Benzopyran and imidazole derivatives useful for stabilizing amyloidogenic immunoglobulin light chains | 斯克利普斯研究所 | 2022-03-01 | — | — | CN | disclosed |