SCHEMBL2435898

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2425575	0.77	ALDH1A1 (0.39)	ALDH1A3ALDH1A1ALDH1A2APPSMN1; SMN2
	SCHEMBL12291868	0.70	APP (0.36)	ALDH1A3ALDH1A1APPSMN1; SMN2HRH3
	SCHEMBL2427073	0.70	RAB9A (0.63)	ALDH1A3ALDH1A1ALDH1A2SMN1; SMN2MAPT
	SCHEMBL2430718	0.69	APP (0.59)	ALDH1A3ALDH1A1ALDH1A2APPSMN1; SMN2
	SCHEMBL2430633	0.69	APP (0.59)	ALDH1A3ALDH1A1ALDH1A2APPSMN1; SMN2
	SCHEMBL21211528	0.67	TDP1 (0.70)	APPCXCR4SMN1; SMN2MAPTLIN28A
	SCHEMBL30191149	0.66	SMN1; SMN2 (0.79)	ALDH1A1APPCXCR4SMN1; SMN2MAPT
	SCHEMBL138261	0.64	SMN1; SMN2 (0.83)	ALDH1A1APPCXCR4SMN1; SMN2MAPT
	SCHEMBL18211842	0.64	NPSR1 (0.63)	ALDH1A1APPCXCR4SMN1; SMN2MAPT
	SCHEMBL30359538	0.63	TDP1 (0.63)	ALDH1A1APPCXCR4SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.