SCHEMBL24359595

SCHEMBL24359595

O=C(O)CC1CCN(CC(c2ccccc2)c2ccccc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
SLC6A3 Q01959 4/20 0.46
SLC6A4 P31645 3/20 0.46
KCNA3 P22001 1/20 0.45
SLC6A2 P23975 3/20 0.44
HTR1A P08908 1/20 0.44
CACNA2D1 P54289 1/20 0.44
CACNA1B Q00975 1/20 0.44
CACNB1 Q02641 1/20 0.44
CACNA1C Q13936 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13960303 0.85 KCNA3 (0.66) KCNA3
SCHEMBL24359592 0.81 MEN1 (0.48) MEN1KMT2ASLC6A3SLC6A4KCNA3
SCHEMBL24433074 0.81 L3MBTL1 (0.51) KCNA3
SCHEMBL13857882 0.79 ALDH1A1 (0.55) MEN1KMT2ACACNA2D1CACNA1BCACNB1
SCHEMBL6747206 0.78 CXCR4 (0.65)
SCHEMBL9020789 0.77 SLC6A4 (0.61) SLC6A3SLC6A4SLC6A2
Lithium Ion SCHEMBL22470269 0.77 ALDH1A1 (0.47) MEN1KMT2AKCNA3
SCHEMBL9906607 0.77 KCNA3 (0.59) MEN1KMT2AKCNA3HTR1ACACNA2D1
Hydrochloric Acid SCHEMBL10944441 0.76 SIGMAR1 (0.61) SLC6A3KCNA3SLC6A2
Hydrochloric Acid SCHEMBL9537230 0.76 BCHE (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230391731-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2023-12-07 US disclosed
EP-4232437-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF Liangjiang Medicine Co., Ltd. (CN) 2023-08-30 EP disclosed
CN-116529252-A Prodrugs for sustained release of therapeutic agents and uses thereof 重庆两江药物研发中心有限公司 2023-08-01 CN disclosed
WO-2022083679-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2022-04-28 WO disclosed
WO-2022083679-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF LIANGJIANG MEDICINE CO., LTD. (CN) 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391731-A1 PRODRUGS FOR SUSTAINED RELEASING THERAPEUTIC AGENTS AND USES THEREOF GRPR, SLC2A8, HPGDS MEN1 1485/4885KMT2A 4380/4885SLC6A3 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.