Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | UQCRB | P14927 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216978 | 0.93 | ALDH1A1 (0.46) | ALDH1A1HSD11B1RAB9ANPC1MAPT | |
| SCHEMBL7578150 | 0.92 | ALDH1A1 (0.42) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL2436033 | 0.90 | ALDH1A1 (0.41) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL2438863 | 0.90 | ALDH1A1 (0.37) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL7578509 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL7575479 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL451538 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL450157 | 0.84 | MMP1 (0.38) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL7741655 | 0.84 | NR3C2 (0.50) | ALDH1A1HSD11B1RAB9ANPC1RECQL | |
| SCHEMBL218620 | 0.84 | CA2 (0.41) | ALDH1A1MAPTKDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078028-B1 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA (US) | 2011-09-07 | — | — | EP | claimed |
| EP-2384457-B1 | COATING COMPOSITIONS | MERCK PATENT GMBH (DE) | 2022-07-06 | — | — | EP | disclosed |