Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24481846 | 0.91 | KDM1A (0.43) | KDM1AOPRM1SMN1; SMN2MAOAMAOB | |
| SCHEMBL14905909 | 0.88 | MEN1 (0.41) | KDM1AOPRM1SMN1; SMN2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL27153631 | 0.86 | MEN1 (0.40) | KDM1AOPRM1SMN1; SMN2MAOAMAOB | |
| SCHEMBL14902474 | 0.85 | OPRM1 (0.36) | KDM1AOPRM1SMN1; SMN2OPRL1KCNH2 | |
| SCHEMBL14902456 | 0.85 | OPRM1 (0.45) | OPRM1SMN1; SMN2OPRL1ALDH1A1KCNH2 | |
| SCHEMBL14902471 | 0.84 | OPRM1 (0.60) | OPRM1SMN1; SMN2OPRL1ALDH1A1HSD17B10 | |
| SCHEMBL14902457 | 0.81 | CYP2D6 (0.46) | OPRM1SMN1; SMN2OPRL1ALDH1A1MEN1 | |
| SCHEMBL4678353 | 0.79 | MAOA (0.48) | KDM1AOPRM1SMN1; SMN2MAOAMAOB | |
| SCHEMBL14902460 | 0.79 | CYP2D6 (0.51) | SMN1; SMN2ALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL14902431 | 0.79 | NPC1 (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |
| WO-2006094201-A2 | SEMICARBAZIDE-SENSITIVE AMIDE OXIDASE INHIBITORS | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| EP-1663954-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL CO. (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20050096360-A1 | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases | LA JOLLA PHARMACEUTICALS COMPANY | 2005-05-05 | — | — | US | disclosed |
| WO-2005014530-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL CO. (US) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096360-A1 | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases | VCAM1, AOC2, AOC3 | KDM1A 452/4885OPRM1 486/4885SMN1; SMN2 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.