SCHEMBL24370049

SCHEMBL24370049

c1ccc(-c2ccccc2-c2ccc(N(c3ccc(-c4ccccc4-c4ccccc4)cc3)c3cccc4sc5c(-c6ccccc6)cccc5c34)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
LIMK1 P53667 2/20 0.39
F9 P00740 1/20 0.33
PARP14 Q460N5 1/20 0.32
APP P05067 1/20 0.31
TNKS O95271 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
SLC9A1 P19634 1/20 0.30
CRHR1 P34998 1/20 0.30
PRKDC P78527 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24369991 0.96 LIMK1 (0.39) ALOX5LIMK1F9PARP14APP
SCHEMBL24370073 0.90 F9 (0.37) ALOX5LIMK1F9APPSLC9A1
SCHEMBL24370079 0.89 F9 (0.36) ALOX5LIMK1F9APPSLC9A1
SCHEMBL24370051 0.89 F9 (0.36) ALOX5LIMK1F9APPSLC9A1
SCHEMBL24472190 0.88 ALOX5 (0.41) ALOX5LIMK1F9PRKDC
SCHEMBL23258279 0.88 ALOX5 (0.38) ALOX5LIMK1F9CRHR1MCL1
SCHEMBL25890620 0.86 ALOX5 (0.36) ALOX5LIMK1PRKDC
SCHEMBL23258262 0.86 ALOX5 (0.39) ALOX5LIMK1F9CRHR1MCL1
SCHEMBL21214777 0.86 F9 (0.39) ALOX5LIMK1F9APPSLC9A1
SCHEMBL25577446 0.86 ALOX5 (0.42) ALOX5LIMK1F9PARP14TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131079-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131079-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME MAOA, AOC1, ALDH1A2 ALOX5 582/4885LIMK1 339/4885F9 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.