SCHEMBL24370188

SCHEMBL24370188

N#Cc1ccc(-n2c3ccccc3c3cc(-c4cc(-n5c6ccccc6c6ccccc65)cc(C(F)(F)F)c4)ccc32)c(-c2ccc(C(F)(F)F)cc2C#N)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33
KIF11 P52732 2/20 0.32
RXRA P19793 1/20 0.31
RXRG P48443 1/20 0.31
ELANE P08246 3/20 0.31
TACR1 P25103 2/20 0.31
PTGER4 P35408 1/20 0.30
PTPN5 P54829 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24369975 0.96 RXRA (0.32) KIF11RXRARXRGELANETACR1
SCHEMBL24370107 0.95 ALOX5AP (0.33) ALOX5APFEN1KIF11RXRARXRG
SCHEMBL24370187 0.94 KIF11 (0.34) ALOX5APFEN1KIF11RXRARXRG
SCHEMBL24370131 0.93 RXRA (0.35) KIF11RXRARXRGELANETACR1
SCHEMBL22985169 0.92 ALOX5AP (0.32) ALOX5APFEN1KIF11
SCHEMBL24370109 0.92 PTPN5 (0.34) ALOX5APFEN1KIF11ELANEPTPN5
SCHEMBL24369734 0.92 KIF11 (0.36) ALOX5APFEN1KIF11ELANEPTGER4
SCHEMBL22985132 0.91 ALOX5AP (0.37) ALOX5APFEN1KIF11RXRARXRG
SCHEMBL22985076 0.91 ALOX5AP (0.38) ALOX5APFEN1KIF11RXRARXRG
SCHEMBL24369767 0.91 ALOX5AP (0.36) ALOX5APFEN1KIF11PTGER4PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SIK3, ORAI3, HIPK3 ALOX5AP 4793/4885FEN1 740/4885KIF11 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.