SCHEMBL24370131

SCHEMBL24370131

N#Cc1ccc(-n2c3ccccc3c3cc(-c4cc(-n5c6ccccc6c6ccccc65)cc(C(F)(F)F)c4)ccc32)c(-c2cc(C#N)ccc2-n2c3ccccc3c3cc(-c4cc(-n5c6ccccc6c6ccccc65)cc(C(F)(F)F)c4)ccc32)c1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.35
RXRG P48443 1/20 0.35
KIF11 P52732 1/20 0.35
TACR1 P25103 2/20 0.34
PTGER4 P35408 1/20 0.33
PDPK1 O15530 1/20 0.33
ICMT O60725 2/20 0.33
ELANE P08246 3/20 0.32
PTPN5 P54829 1/20 0.32
PGR P06401 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24369941 0.95 RXRA (0.36) RXRARXRGKIF11TACR1PTGER4
SCHEMBL24369975 0.94 RXRA (0.32) RXRARXRGKIF11TACR1PTGER4
SCHEMBL24369787 0.94 PGR (0.34) RXRARXRGKIF11TACR1PTGER4
SCHEMBL24370441 0.94 ELANE (0.33) RXRARXRGKIF11TACR1PTGER4
SCHEMBL24370118 0.93 ELANE (0.38) RXRARXRGKIF11TACR1PTGER4
SCHEMBL24370061 0.93 KIF11 (0.31) RXRARXRGKIF11TACR1PTGER4
SCHEMBL24370188 0.93 ALOX5AP (0.33) RXRARXRGKIF11TACR1PTGER4
SCHEMBL20849277 0.93 KIF11 (0.37) RXRARXRGKIF11TACR1PTGER4
SCHEMBL20849579 0.92 RXRA (0.35) RXRARXRGKIF11TACR1PTGER4
SCHEMBL24370207 0.91 PTGER4 (0.33) RXRARXRGTACR1PTGER4PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SIK3, ORAI3, HIPK3 RXRA 4688/4885RXRG 4524/4885KIF11 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.