SCHEMBL24370441

SCHEMBL24370441

N#Cc1ccc(-n2c3ccccc3c3cc(-c4cc(-n5c6ccccc6c6ccccc65)cc(C(F)(F)F)c4)ccc32)c(-c2ccc(C#N)cc2C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.33
KIF11 P52732 2/20 0.32
RXRA P19793 1/20 0.32
RXRG P48443 1/20 0.32
TACR1 P25103 2/20 0.31
PTGER4 P35408 1/20 0.31
PDK2 Q15119 1/20 0.30
PDPK1 O15530 1/20 0.30
AR P10275 2/20 0.30
ICMT O60725 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24370131 0.94 RXRA (0.35) ELANEKIF11RXRARXRGTACR1
SCHEMBL24370448 0.93 KIF11 (0.33) KIF11PTGER4PDK2PDPK1AR
SCHEMBL22985480 0.92 KIF11 (0.31) ELANEKIF11RXRARXRGTACR1
SCHEMBL24369774 0.92 KIF11 (0.35) KIF11PTGER4PDK2PDPK1AR
SCHEMBL24369975 0.91 RXRA (0.32) ELANEKIF11RXRARXRGTACR1
SCHEMBL22985336 0.91 AR (0.33) KIF11RXRARXRGTACR1PTGER4
SCHEMBL22985247 0.91 AR (0.34) KIF11RXRARXRGTACR1PTGER4
SCHEMBL24369941 0.90 RXRA (0.36) ELANEKIF11RXRARXRGTACR1
SCHEMBL24370442 0.90 PDK2 (0.35) ELANEKIF11PTGER4PDK2PDPK1
SCHEMBL24370445 0.89 KIF11 (0.38) KIF11PTGER4PDK2PDPK1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SIK3, ORAI3, HIPK3 ELANE 2051/4885KIF11 3200/4885RXRA 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.