Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | UQCRB | P14927 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434949 | 0.94 | ALDH1A1 (0.44) | HSD11B1ALDH1A1UQCRBNPC1RAB9A | |
| Trifluoromethanesulfonic Acid SCHEMBL3136704 | 0.92 | HSD11B1 (0.41) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 | |
| Trifluoromethanesulfonic Acid SCHEMBL51512 | 0.92 | HSD11B1 (0.41) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 | |
| SCHEMBL29745785 | 0.91 | HSD11B1 (0.40) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 | |
| SCHEMBL2437032 | 0.90 | HSD11B1 (0.35) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 | |
| SCHEMBL2435494 | 0.88 | HSD11B1 (0.38) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 | |
| SCHEMBL2438820 | 0.88 | HSD11B1 (0.38) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 | |
| SCHEMBL7578509 | 0.87 | ALDH1A1 (0.44) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 | |
| SCHEMBL2437867 | 0.87 | GPR3 (0.40) | HSD11B1ALDH1A1PTPN1CA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL36543 | 0.85 | ALDH1A1 (0.46) | HSD11B1ALDH1A1HSD17B3UQCRBHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078028-B1 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA (US) | 2011-09-07 | — | — | EP | claimed |
| EP-2384457-B1 | COATING COMPOSITIONS | MERCK PATENT GMBH (DE) | 2022-07-06 | — | — | EP | disclosed |