Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10210075 | 0.84 | ALDH1A1 (0.43) | HSD17B10ALOX15CYP3A4GAAKDM4E | |
| SCHEMBL23005772 | 0.77 | HSD17B10 (0.52) | HSD17B10ALOX15CYP3A4CA12CA1 | |
| SCHEMBL140666 | 0.77 | CA12 (0.69) | HSD17B10ALOX15XDHCA12CA1 | |
| SCHEMBL29433281 | 0.77 | CA12 (0.69) | HSD17B10ALOX15XDHCA12CA1 | |
| SCHEMBL13816253 | 0.76 | MAPT (0.40) | HSD17B10ALOX15GAAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL2972630 | 0.76 | CA12 (0.67) | HSD17B10ALOX15XDHCA12CA1 | |
| SCHEMBL23155658 | 0.75 | ALOX15 (0.50) | HSD17B10ALOX15CYP3A4CA12CA1 | |
| SCHEMBL13008247 | 0.75 | ALOX15 (0.50) | HSD17B10ALOX15CYP3A4CA12CA1 | |
| SCHEMBL25990194 | 0.73 | ALDH1A1 (0.48) | HSD17B10ALOX15CYP3A4XDHCA12 | |
| SCHEMBL8368541 | 0.73 | CYP19A1 (0.43) | HSD17B10ALOX15CYP3A4CA14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084741-A1 | CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-28 | — | — | WO | disclosed |