SCHEMBL24372286

SCHEMBL24372286

N#Cc1ccc(C2OCCO2)s1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM1A O60341 1/20 0.32
PGR P06401 1/20 0.31
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL5005912 0.72
SCHEMBL18921367 0.70 PGR (0.30) ALDH1A1MAPTRECQLSMN1; SMN2PGR
SCHEMBL24228097 0.70 GABRP (0.35) ALDH1A1MAPT
SCHEMBL6751422 0.69
SCHEMBL20042464 0.69 ALDH1A1 (0.40) ALDH1A1MAPTSMN1; SMN2
SCHEMBL19255873 0.69
2,5-Thiophenedinitrile SCHEMBL996528 0.68
Bromide SCHEMBL27665996 0.68
SCHEMBL24228023 0.68 KDM4E (0.37) ALDH1A1RECQLSMN1; SMN2
SCHEMBL15783791 0.67 MEN1 (0.38) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988548-B1 OXADIAZOLE COMPOUND OR SALTS THEREOF, AND AGRICULTURAL/HORTICULTURAL BACTERICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME NIHON NOHYAKU CO LTD (JP) 2026-01-28 EP disclosed
US-12171231-B2 Oxadiazole compounds or salts thereof, agrohorticultural fungicides containing the compounds, and methods of using the same NIHON NOHYAKU CO., LTD. (JP) 2024-12-24 US disclosed
CN-114585620-B Oxadiazole compounds or salts thereof, agrohorticultural fungicides containing the same, and methods of use thereof 日本农药株式会社 2024-02-23 CN disclosed
US-20220248675-A1 OXADIAZOLE COMPOUNDS OR SALTS THEREOF, AGROHORTICULTURAL FUNGICIDES CONTAINING THE COMPOUNDS, AND METHODS OF USING THE SAME NIHON NOHYAKU CO., LTD. (JP) 2022-08-11 US disclosed
WO-2022138017-A1 OXADIAZOLE COMPOUND OR SALT THEREOF, AND AGRICULTURAL/HORTICULTURAL MICROBICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME 日本農薬株式会社 2022-06-30 WO disclosed
CN-114585620-A Oxadiazole compound or salt thereof, agricultural/horticultural fungicide containing the same, and method for using the same 日本农药株式会社 2022-06-03 CN disclosed
EP-3988548-A1 OXADIAZOLE COMPOUND OR SALTS THEREOF, AND AGRICULTURAL/HORTICULTURAL BACTERICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME Nihon Nohyaku Co., Ltd. (JP) 2022-04-27 EP disclosed
EP-3988548-A1 OXADIAZOLE COMPOUND OR SALTS THEREOF, AND AGRICULTURAL/HORTICULTURAL BACTERICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME Nihon Nohyaku Co., Ltd. (JP) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220248675-A1 OXADIAZOLE COMPOUNDS OR SALTS THEREOF, AGROHORTICULTURAL FUNGICIDES CONTAINING THE COMPOUNDS, AND METHODS OF USING THE SAME CBR3, OXA1L, NOX3 ALDH1A1 823/4885MAPT 3209/4885RECQL 962/4885
US-12171231-B2 Oxadiazole compounds or salts thereof, agrohorticultural fungicides containing the compounds, and methods of using the same CBR3, OXA1L, NOX3 ALDH1A1 823/4885MAPT 3209/4885RECQL 962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.