SCHEMBL24372629

SCHEMBL24372629

c1ccc(N(c2ccc3c(c2)oc2ccccc23)c2ccc3oc4ccccc4c3c2)c(-c2ccc3ccc4c5ccccc5ccc4c3c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 9/20 0.35
▸ MAPT P10636 6/20 0.35
▸ HPGD P15428 5/20 0.35
▸ TSHR P16473 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35
▸ GLA P06280 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ HNF4A P41235 1/20 0.34
▸ ALDH1A1 P00352 8/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ CASP1 P29466 1/20 0.34
▸ CASP7 P55210 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ HSP90AB1 P08238 1/20 0.34
▸ KMT2A Q03164 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ AHR P35869 2/20 0.34
▸ NPC1 O15118 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24373167 0.93 AHR (0.34) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL24372475 0.93 KDM4E (0.35) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL24372695 0.91 KDM4E (0.40) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL24965438 0.91 HSP90AA1 (0.35) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL24373192 0.91 KDM4E (0.36) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL26056619 0.89 PLA2G2A (0.34) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL24963742 0.89 MCL1 (0.36) KDM4EMAPTHPGDHSD17B10ALDH1A1
SCHEMBL24965802 0.88 HSP90AA1 (0.35) KDM4EMAPTHPGDALDH1A1HSP90AA1
SCHEMBL24965486 0.88 ALOX5 (0.37) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL27324224 0.88 KDM4E (0.32) KDM4EMAPTHPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 — — US disclosed
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 — — US disclosed
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-11 — — US disclosed
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-11 — — US disclosed
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-04 — — US disclosed
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-04 — — US disclosed
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, SOD1, ELAVL1 KDM4E 2176/4885MAPT 2415/4885HPGD 4548/4885
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE ELAVL1, LIMS1, ZNF436-AS1 KDM4E 1563/4885MAPT 1472/4885HPGD 4467/4885
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, L1CAM, EPHA6 KDM4E 2955/4885MAPT 1927/4885HPGD 4641/4885
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, TERT, LIMS1 KDM4E 3373/4885MAPT 2033/4885HPGD 4072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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