Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21263632 | 0.79 | — | — | |
| SCHEMBL24933454 | 0.73 | — | — | |
| SCHEMBL30600426 | 0.70 | ALDH1A1 (0.68) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL24652759 | 0.65 | — | — | |
| SCHEMBL24652651 | 0.62 | — | — | |
| SCHEMBL24652646 | 0.62 | — | — | |
| SCHEMBL172044 | 0.59 | CYP3A4 (0.36) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL189622 | 0.59 | ALDH1A1 (0.59) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL27759119 | 0.59 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL4871529 | 0.57 | ALDH1A1 (0.55) | MEN1ALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |