SCHEMBL2437352

SCHEMBL2437352

NC(=O)OC1C2CCCCC21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.34
ATM Q13315 1/20 0.33
ALOX5 P09917 2/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
METAP2 P50579 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17814881 0.79 RAB9A (0.33) ATM
SCHEMBL3979936 0.77 POLB (0.32) EPHX1CES2CES1
SCHEMBL3983989 0.75 CES2 (0.36) EPHX1CES2CES1
SCHEMBL112091 0.74
SCHEMBL9800024 0.74 SERPINE1 (0.41) EPHX1ATMALOX5CES2CES1
SCHEMBL10867518 0.74 SERPINE1 (0.41) EPHX1ATMALOX5CES2CES1
SCHEMBL26099348 0.73 ATM (0.32) ATM
SCHEMBL21144296 0.73 ATM (0.32) ATM
SCHEMBL26099346 0.73 ATM (0.32) ATM
SCHEMBL1416705 0.72 EPHX1 (0.50) EPHX1ATMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3383200-B1 COMPOSITIONS SYMRISE AG (DE) 2019-11-06 EP claimed
EP-3383200-A1 SUBSTANCE MIXTURES Symrise AG (DE) 2018-10-10 EP claimed
WO-2017092796-A1 SUBSTANCE MIXTURES SYMRISE AG (DE) 2017-06-08 WO claimed
EP-3383200-B1 COMPOSITIONS SYMRISE AG (DE) 2019-11-06 EP disclosed
EP-3383200-A1 SUBSTANCE MIXTURES Symrise AG (DE) 2018-10-10 EP disclosed
WO-2017092796-A1 SUBSTANCE MIXTURES SYMRISE AG (DE) 2017-06-08 WO disclosed
EP-2737807-B1 Use of nitrogen-containing derivatives of cinnamic acid as flavourants SYMRISE AG (DE) 2017-04-05 EP disclosed
EP-2614727-B1 N-Nonanoylvanillylamine as an appetite reduction agent and as a means for generating the feeling of being full and corresponding orally consumable products and method SYMRISE AG (DE) 2016-09-07 EP disclosed
EP-2962679-A1 Use of tetrahydrofuranlignans Symrise AG (DE) 2016-01-06 EP disclosed
EP-2918271-A1 Aromatic alkenoic acid derivatives as aroma compounds Symrise AG (DE) 2015-09-16 EP disclosed
WO-2014083202-A1 USE OF CINNAMIC ACID DERIVATIVES CONTAINING NITROGEN AS FLAVOURING AGENTS SYMRISE AG (DE) 2014-06-05 WO disclosed
EP-2135516-B1 Neo-menthyl derivatives as flavourings SYMRISE AG (DE) 2012-08-15 EP disclosed
EP-2064959-B1 Aromatic Neomenthylamides as flavouring agents SYMRISE AG (DE) 2012-07-25 EP disclosed
EP-2168442-B1 Geranylamine derivatives of oxalic acid SYMRISE AG (DE) 2011-11-09 EP disclosed
EP-2156748-B1 Composition for reducing the NaCl content in food SYMRISE AG (DE) 2011-09-21 EP disclosed
EP-1989944-B1 Substituted cyclopropane carbolic acid(3-methyl-cyclohexyl)amides as taste substances SYMRISE GMBH & CO KG (DE) 2010-06-02 EP disclosed
EP-2168442-A2 Geranylamine derivatives of oxalic acid Symrise GmbH & Co. KG (DE) 2010-03-31 EP disclosed
EP-2135516-A1 Neo-menthyl derivatives as flavourings Symrise GmbH & Co. KG (DE) 2009-12-23 EP disclosed
EP-2064959-A1 Aromatic Neomenthylamides as flavouring agents Symrise GmbH & Co. KG (DE) 2009-06-03 EP disclosed
EP-1989944-A1 Substituted cyclopropane carbolic acid(3-methyl-cyclohexyl)amides as taste substances Symrise GmbH & Co. KG (DE) 2008-11-12 EP disclosed