Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983989 | 0.97 | CES2 (0.36) | POLBKDM4EL3MBTL1CES2CES1 | |
| SCHEMBL3983190 | 0.95 | MEN1 (0.33) | L3MBTL1 | |
| SCHEMBL2437352 | 0.77 | EPHX1 (0.34) | CES2CES1EPHX1 | |
| SCHEMBL3987567 | 0.75 | NPC1 (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL3984069 | 0.73 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL933668 | 0.73 | CA1 (0.31) | — | |
| SCHEMBL8644323 | 0.73 | CA1 (0.31) | — | |
| SCHEMBL1554143 | 0.73 | CA1 (0.31) | — | |
| SCHEMBL2936710 | 0.73 | CA1 (0.31) | — | |
| SCHEMBL8932121 | 0.73 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562575-B1 | FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY | ABBOTT LAB (US) | 2009-05-20 | — | — | EP | claimed |