SCHEMBL24374079

SCHEMBL24374079

Clc1ccc(-c2ccc(-n3c4ccccc4c4ccc5ccccc5c43)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
BIRC5 O15392 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
CYP1A2 P05177 5/20 0.38
CYP1A1 P04798 4/20 0.38
CYP1B1 Q16678 4/20 0.38
PTGS2 P35354 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HDAC4 P56524 1/20 0.35
BMX P51813 1/20 0.35
USP14 P54578 1/20 0.35
EGFR P00533 1/20 0.34
ERBB2 P04626 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24374014 0.95 KDM4E (0.44) KDM4EATML3MBTL1BIRC5SMN1; SMN2
SCHEMBL14134234 0.92 KDM4E (0.47) KDM4EATML3MBTL1CYP1A2MAPT
SCHEMBL24374358 0.90 CYP2A6 (0.39) KDM4EATML3MBTL1BIRC5CYP1A2
SCHEMBL24949660 0.88 CYP1A2 (0.39) KDM4EATML3MBTL1BIRC5CYP1A2
SCHEMBL23195211 0.88 CYP1A2 (0.40) KDM4EATML3MBTL1CYP1A2CYP1A1
SCHEMBL21450430 0.87 L3MBTL1 (0.45) KDM4EATML3MBTL1SMN1; SMN2NPC1
SCHEMBL21566451 0.87 L3MBTL1 (0.46) KDM4EATML3MBTL1SMN1; SMN2NPC1
SCHEMBL12249842 0.86 EGFR (0.39) KDM4EATML3MBTL1SMN1; SMN2NPC1
SCHEMBL15138711 0.85 CYP1A1 (0.42) KDM4EATML3MBTL1SMN1; SMN2NPC1
SCHEMBL17943387 0.85 L3MBTL1 (0.44) KDM4EATML3MBTL1CYP1A2CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-11-02 US disclosed
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-11-02 US disclosed
WO-2023085877-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2023-05-19 WO disclosed
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
WO-2023003403-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
WO-2022086297-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, PER2 KDM4E 2382/4885ATM 2287/4885L3MBTL1 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.