Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22140511 | 0.90 | PDGFRB (0.37) | MAPTMAPK1POLBSIRT6PDGFRB | |
| SCHEMBL22140402 | 0.86 | KDM4E (0.42) | MAPTPDGFRBKDRABL1CFTR | |
| SCHEMBL22140527 | 0.81 | MAPT (0.42) | MAPTMAPK1POLBSIRT6PDGFRB | |
| SCHEMBL26174042 | 0.76 | KDM4E (0.40) | MAPTMAPK1POLBKDM4EALDH1A1 | |
| SCHEMBL29679513 | 0.75 | SIRT6 (0.48) | MAPTPOLBSIRT6PDGFRBFGFR1 | |
| SCHEMBL1640894 | 0.75 | SIRT6 (0.48) | MAPTPOLBSIRT6PDGFRBFGFR1 | |
| SCHEMBL23988963 | 0.74 | ABL1 (0.33) | PDGFRBKDRABL1CFTRALOX5AP | |
| SCHEMBL2895340 | 0.73 | PDGFRB (0.50) | MAPTPOLBSIRT6PDGFRBFGFR1 | |
| SCHEMBL5168499 | 0.73 | KDM4E (0.49) | MAPTSIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL29878477 | 0.72 | TDP1 (0.43) | MAPTMAPK1POLBSIRT6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753377-B2 | Crystal form of 2-methyl-2-propanol and amino-substituted aryl compound | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-09-12 | — | — | US | disclosed |
| US-20230174489-A1 | CRYSTAL FORM OF 2-METHYL-2-PROPANOL AND AMINO-SUBSTITUTED ARYL COMPOUND | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-06-08 | — | — | US | disclosed |
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174489-A1 | CRYSTAL FORM OF 2-METHYL-2-PROPANOL AND AMINO-SUBSTITUTED ARYL COMPOUND | CYP51A1, CYP4A11, CYP11B2 | MAPT 642/4885MAPK1 444/4885POLB 3144/4885 |
| US-11753377-B2 | Crystal form of 2-methyl-2-propanol and amino-substituted aryl compound | CYP51A1, CYP4A11, CYP11B2 | MAPT 642/4885MAPK1 444/4885POLB 3144/4885 |
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ALDH1A2, ALDH1A3, NR2E3 | MAPT 231/4885MAPK1 4627/4885POLB 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.