Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.32 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24377932 | 0.74 | SLC6A4 (0.62) | SLC6A4 | |
| SCHEMBL24377636 | 0.74 | SLC6A4 (0.45) | SLC6A4 | |
| SCHEMBL29546618 | 0.74 | SLC6A4 (0.62) | SLC6A4 | |
| SCHEMBL22128362 | 0.73 | IMPDH2 (0.47) | PIM1PIM2SLC6A4 | |
| SCHEMBL20200677 | 0.68 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGMAPK14 | |
| SCHEMBL18988775 | 0.68 | PIK3CA (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGMAPK14 | |
| SCHEMBL14529647 | 0.68 | AR (0.43) | PIM1PIM2SLC6A4MAPK14JAK3 | |
| SCHEMBL23536642 | 0.68 | PIM1 (0.42) | PIM1PIM2PIK3CDPIK3CAMAPK14 | |
| SCHEMBL2431741 | 0.68 | JAK3 (0.36) | PIM1PIM2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30632800 | 0.66 | PRKAB2 (0.44) | PIK3CDPIK3CAPIK3CBPRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083560-A1 | TYK2 SELECTIVE INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 | 2022-04-28 | — | — | WO | disclosed |