Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438488 | 0.81 | CYP19A1 (0.37) | CYP3A4KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL31341048 | 0.73 | RAB9A (0.57) | KDM4EALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL13377800 | 0.72 | PDE10A (0.67) | PDE10ACYP3A4CYP2E1CYP2A6CYP2C9 | |
| SCHEMBL18157874 | 0.72 | SMN1; SMN2 (0.55) | PDE10ACYP3A4CYP2E1CYP2A6CYP2C9 | |
| SCHEMBL24378644 | 0.72 | ECE1 (0.42) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL30574726 | 0.70 | PDE10A (0.46) | PDE10ACYP3A4CYP2E1CYP2A6CYP2C9 | |
| SCHEMBL8198560 | 0.69 | CYP3A4 (0.60) | PDE10ACYP3A4CYP2E1CYP2A6CYP2C9 | |
| SCHEMBL6840531 | 0.68 | PDE10A (0.52) | PDE10ACYP3A4CYP2E1CYP2A6CYP2C9 | |
| SCHEMBL7905176 | 0.67 | CYP3A4 (0.58) | PDE10ACYP3A4CYP2E1CYP2A6CYP2C9 | |
| SCHEMBL1673128 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036718-A | ALK5 inhibitor and preparation method and application thereof | 安炎达医药技术(广州)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| WO-2022086993-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-1046275-C | 2-methoxyiminophenyl-N-methylacetamide derivatives, process for their preparation, their use and compositions containing them | BASF AG (DE) | 1999-11-10 | — | — | CN | disclosed |
| CN-1118165-A | Ortho-substituted 2-methoxyiminophenylacetic acid methylamides | BASF AG (DE) | 1996-03-06 | — | — | CN | disclosed |