Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795092 | 0.80 | ALDH1A1 (0.47) | KDM4ERAB9AKMT2AMAPTMEN1 | |
| SCHEMBL1673128 | 0.75 | — | — | |
| SCHEMBL31341048 | 0.69 | RAB9A (0.57) | CYP19A1KDM4ERAB9AKMT2AMAPT | |
| Bromide SCHEMBL3354419 | 0.69 | KMT2A (0.58) | RAB9AKMT2AMAPTMEN1MKNK2 | |
| SCHEMBL1782526 | 0.68 | HSP90AA1 (0.46) | RAB9ACYP1A1CYP1B1 | |
| SCHEMBL28116569 | 0.68 | FBP1 (0.31) | — | |
| SCHEMBL2458453 | 0.67 | CCR1 (0.41) | KDM4ERAB9AKMT2AMAPTMEN1 | |
| SCHEMBL6330575 | 0.67 | HSP90AA1 (0.44) | RAB9ACYP1A1CYP1B1 | |
| SCHEMBL633330 | 0.67 | KDM4E (0.44) | KDM4ERAB9AMAPTL3MBTL1HPGD | |
| SCHEMBL28408851 | 0.66 | KDM4E (0.33) | KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976605-A1 | METHODS FOR MAKING THISZOLYLPYRAZOLE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR | Bantam Pharmaceutical, LLC (US) | 2022-04-06 | — | — | EP | disclosed |