SCHEMBL24378768

SCHEMBL24378768

Cc1ccc(C(C)C)c(OC(=O)CI)c1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18256026 0.87 LMNA (0.56) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL30464895 0.87 LMNA (0.56) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL249686 0.85 ALDH1A1 (0.56) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL24596040 0.84 LMNA (0.51) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL11578073 0.84 LMNA (0.53) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL22580428 0.84 L3MBTL1 (0.56) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL29910683 0.84 LMNA (0.53) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL23707017 0.84 LMNA (0.53) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL19919418 0.84 LMNA (0.53) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL30464896 0.84 LMNA (0.53) LMNAL3MBTL1KDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022084916-A1 COMPOUNDS FOR USE IN TREATING CORONAVIRUS INFECTION AND AFRICAN SWINE FEVER VIRUS INFECTION RHEA GENETICS PTE. LTD. (SG) 2022-04-28 WO disclosed