SCHEMBL23707017

SCHEMBL23707017

Cc1ccc(C(C)C)c(OC(=O)CCCCC(=O)Oc2cc(C)ccc2C(C)C)c1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30464896 1.00 LMNA (0.53) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL27948943 0.95 LMNA (0.53) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL28980175 0.94 ALOX15 (0.52) LMNAL3MBTL1ALDH1A1
SCHEMBL30464895 0.93 LMNA (0.56) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL18256026 0.93 LMNA (0.56) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL17073977 0.93 ALOX15 (0.51) LMNAL3MBTL1ALDH1A1
SCHEMBL28080449 0.93 ALOX15 (0.51) LMNAL3MBTL1ALDH1A1
SCHEMBL15456833 0.93 ALOX15 (0.51) LMNAL3MBTL1ALDH1A1
SCHEMBL23707002 0.93 LMNA (0.48) LMNAL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL249973 0.92 ALDH1A1 (0.52) LMNAL3MBTL1KDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345932-A1 MONOTERPENOID/PHENYLPROPANOID CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS SEED TREATMENTS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-11-02 US disclosed
US-20230345932-A1 MONOTERPENOID/PHENYLPROPANOID CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS SEED TREATMENTS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-11-02 US disclosed
US-11696581-B2 Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as seed treatments KITTRICH CORPORATION (US) 2023-07-11 US disclosed
US-11696581-B2 Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as seed treatments KITTRICH CORPORATION (US) 2023-07-11 US disclosed
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS KITTRICH CORPORATION 2023-06-22 US disclosed
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS KITTRICH CORPORATION 2023-06-22 US disclosed
US-20210235693-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS SEED TREATMENTS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696581-B2 Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as seed treatments ALOX5, PTGES, ALOX15 LMNA 1679/4885L3MBTL1 1183/4885KDM4E 1470/4885
US-20230189802-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS BAITS CYP51A1, CYP4A22, ACHE LMNA 2776/4885L3MBTL1 709/4885KDM4E 1496/4885
US-20230345932-A1 MONOTERPENOID/PHENYLPROPANOID CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS SEED TREATMENTS PTGES, ALOX5, GSTO1 LMNA 1656/4885L3MBTL1 1167/4885KDM4E 1594/4885
US-20210235693-A1 MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS SEED TREATMENTS ALOX5, PTGES, ALOX15 LMNA 1679/4885L3MBTL1 1183/4885KDM4E 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.