Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23918398 | 0.94 | POLB (0.50) | KMT2APOLBMEN1ALDH1A1FEN1 | |
| SCHEMBL23918383 | 0.84 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1CASP3TSHR | |
| SCHEMBL23918716 | 0.84 | MEN1 (0.42) | KMT2APOLBMEN1ALDH1A1CASP3 | |
| SCHEMBL29428315 | 0.83 | ALDH1A1 (0.41) | KMT2APOLBMEN1ALDH1A1FEN1 | |
| SCHEMBL29428378 | 0.83 | ALDH1A1 (0.41) | KMT2APOLBMEN1ALDH1A1FEN1 | |
| SCHEMBL23918370 | 0.81 | ALDH1A1 (0.41) | KMT2APOLBMEN1ALDH1A1FEN1 | |
| SCHEMBL23918744 | 0.80 | MEN1 (0.39) | KMT2APOLBMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29428200 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1CASP3TSHR | |
| SCHEMBL23918386 | 0.74 | FEN1 (0.39) | KMT2APOLBMEN1ALDH1A1FEN1 | |
| SCHEMBL23918389 | 0.74 | LIPG (0.46) | KMT2APOLBMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319324-B2 | Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319324-B2 | Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors | P2RX3, P2RX1, P2RX5 | KMT2A 4618/4885POLB 2313/4885MEN1 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.