Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | FCER2 | P06734 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20880680 | 0.91 | CTSS (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25000472 | 0.91 | MMP1 (0.56) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL18513842 | 0.90 | CTSS (0.54) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25773989 | 0.90 | CTSS (0.52) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25976737 | 0.88 | CTSS (0.55) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25973359 | 0.88 | OPRD1 (0.49) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25751083 | 0.88 | CTSS (0.50) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL27461127 | 0.88 | OPRD1 (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL15853500 | 0.85 | ACE (0.56) | OPRD1OPRM1OPRK1MMP2MMP9 | |
| SCHEMBL27381707 | 0.85 | OPRD1 (0.53) | OPRD1OPRM1OPRK1CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3991754-A1 | ANTIBODY-DRUG CONJUGATE, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. (CN) | 2022-05-04 | — | — | EP | disclosed |