Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042469 | 0.90 | OPRD1 (0.52) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL6828134 | 0.90 | OPRD1 (0.52) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL7211697 | 0.90 | OPRD1 (0.52) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL20880680 | 0.89 | CTSS (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25452475 | 0.89 | OPRD1 (0.51) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL30939437 | 0.89 | OPRD1 (0.51) | OPRD1OPRM1OPRK1CTSSCTSL | |
| Hydrochloric Acid SCHEMBL30333426 | 0.89 | OPRD1 (0.51) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL21437346 | 0.89 | OPRD1 (0.51) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL18515809 | 0.89 | OPRD1 (0.51) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL29590936 | 0.89 | OPRD1 (0.51) | OPRD1OPRM1OPRK1CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143859-C | Camptothecin derivative and its preparation | ������ҩ��ʽ���� | 2004-03-31 | — | — | CN | disclosed |
| CN-1075501-C | Camptothecin derivatives, preparation method, intermediate and application | TANABE SEIYAKU CO (JP) | 2001-11-28 | — | — | CN | disclosed |
| CN-1308078-A | Camptothecin derivative and its preparation | TANADE SEIYAKU CO LTD (JP) | 2001-08-15 | — | — | CN | disclosed |