Metrizamide

Metrizamide

SCHEMBL24383

CC(=O)Nc1c(I)c(C(=O)N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2O)c(I)c(N(C)C(C)=O)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
KDM4E B2RXH2 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
HK2 P52789 6/20 0.41
HK1 P19367 5/20 0.41
LGALS3 P17931 1/20 0.38
MAPK1 P28482 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CD69 Q07108 1/20 0.33
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.33
CHIA Q9BZP6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metrizamide SCHEMBL1650311 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL16984723 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL24382 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL8678604 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL11048850 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL433082 0.87 LMNA (0.76) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL17909957 0.87 LMNA (0.75) LMNAKDM4ECYP2D6CYP2C19HK2
Iohexol SCHEMBL28086756 0.85 LMNA (0.73) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL18923658 0.84 LMNA (0.72) LMNAKDM4ECYP2D6CYP2C19HK2
Ioxaglic Acid SCHEMBL28143605 0.84 LMNA (0.70) LMNAKDM4ECYP2D6CYP2C19HK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7056 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101973-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-15 WO claimed
US-20260125517-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-07 US claimed
US-12616681-B2 Compositions and methods for treating renal injury CASE WESTERN RESERVE UNIVERSITY (US) 2026-05-05 US claimed
WO-2026090138-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO claimed
US-20260108635-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 US claimed
EP-4683579-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC Yeung, Jeffrey E. (US) 2026-01-28 EP claimed
EP-4656210-A1 COMPOSITE HYDROGELS FOR TREATING VASCULAR DEFECTS Covidien LP (US) 2025-12-03 EP claimed
WO-2025226850-A1 HYDROGEL COMPOSITIONS FOR TREATING VASCULAR DEFECTS COVIDIEN LP (US) 2025-10-30 WO claimed
US-20250312520-A1 INJECTABLE BIOPOLYMER COMPOSITIONS AND ASSOCIATED SYSTEMS AND METHODS COVIDIEN LP 2025-10-09 US claimed
US-12364793-B2 Injectable biopolymer compositions and associated systems and methods COVIDIEN LP (US) 2025-07-22 US claimed
US-4795741-A Compositions for therapeutic percutaneous embolization and the use thereof BIOMATRIX, INC. (US) 1989-01-03 US claimed
EP-0291177-A2 Novel compositions for percutaneous embolization Biomatrix, Inc. (US) 1988-11-17 EP claimed
EP-0269520-A2 Retrovirus of the type HIV-2, susceptible to provoke AIDS, and its antigenic and nucleic-acid constituents INSTITUT PASTEUR (FR) 1988-06-01 EP claimed
EP-0239425-A1 Retrovirus of the type HIV-2 capable of inducing AIDS, and the antigenic and nucleic acid components thereof INSTITUT PASTEUR (FR) 1987-09-30 EP claimed
WO-1987004459-A1 RETROVIRUS OF THE HIV-2 TYPE SUSCEPTIBLE OF INDUCING AIDS, AND ITS ANTIGENIC AND NUCLEIC CONSTITUENTS INSTITUT PASTEUR (FR) 1987-07-30 WO claimed
US-4640785-A Separation of lymphocytes and monocytes from blood samples BECTON DICKINSON AND COMPANY (US) 1987-02-03 US claimed
EP-0190488-A1 Separation of lymphocytes and monocytes from blood samples Becton, Dickinson and Company (US) 1986-08-13 EP claimed
US-4455292-A Radiological contrast composition and methods BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1984-06-19 US claimed
US-4327734-A Therapeutic method of use for miniature detachable balloon catheter BECTON, DICKINSON AND COMPANY, A CORP. OF NJ 1982-05-04 US claimed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US claimed