Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HK2 | P52789 | 6/20 | 0.41 |
| ▸ | HK1 | P19367 | 5/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metrizamide SCHEMBL1650311 | 1.00 | LMNA (1.00) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Metrizamide SCHEMBL16984723 | 1.00 | LMNA (1.00) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Metrizamide SCHEMBL24383 | 1.00 | LMNA (1.00) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Metrizamide SCHEMBL24382 | 1.00 | LMNA (1.00) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Metrizamide SCHEMBL11048850 | 1.00 | LMNA (1.00) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Metrizamide SCHEMBL433082 | 0.87 | LMNA (0.76) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Metrizamide SCHEMBL17909957 | 0.87 | LMNA (0.75) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Iohexol SCHEMBL28086756 | 0.85 | LMNA (0.73) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL18923658 | 0.84 | LMNA (0.72) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| Ioxaglic Acid SCHEMBL28143605 | 0.84 | LMNA (0.70) | LMNAKDM4ECYP2D6CYP2C19HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773217-A | USING CYTOSTATIC FACTOR | BRANDEIS UNIVERSITY (US) | 1998-06-30 | — | — | US | disclosed |
| US-5651992-A | In vitro activation of human fetal cells | BRANDEIS UNIVERSITY (US) | 1997-07-29 | — | — | US | disclosed |
| US-5480772-A | SEPARATION OF NUCLEUS FROM ERYTHROCYTES USING PROTEASE AND NONIONIC DETERGENTS, CONTACTING WITH CYTOSTATIC FACTOR EXTRACT AND PRETREATMENT WITH ACTIVATING EGG EXTRACT | BRANDEIS UNIVERSITY (US) | 1996-01-02 | — | — | US | disclosed |