Metrizamide

Metrizamide

SCHEMBL1650311

CC(=O)Nc1c(I)c(C(=O)NC2C(O)[C@H](O)C(CO)O[C@@H]2O)c(I)c(N(C)C(C)=O)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
KDM4E B2RXH2 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
HK2 P52789 6/20 0.41
HK1 P19367 5/20 0.41
LGALS3 P17931 1/20 0.38
MAPK1 P28482 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CD69 Q07108 1/20 0.33
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.33
CHIA Q9BZP6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metrizamide SCHEMBL16984723 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL24383 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL24382 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL8678604 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL11048850 1.00 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL433082 0.87 LMNA (0.76) LMNAKDM4ECYP2D6CYP2C19HK2
Metrizamide SCHEMBL17909957 0.87 LMNA (0.75) LMNAKDM4ECYP2D6CYP2C19HK2
Iohexol SCHEMBL28086756 0.85 LMNA (0.73) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL18923658 0.84 LMNA (0.72) LMNAKDM4ECYP2D6CYP2C19HK2
Ioxaglic Acid SCHEMBL28143605 0.84 LMNA (0.70) LMNAKDM4ECYP2D6CYP2C19HK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240200037-A1 METHOD FOR PRODUCING VIRUS PARTICLES THE UNIVERSITY OF TOKYO (JP) 2024-06-20 US claimed
EP-4324907-A1 METHOD FOR PRODUCING VIRUS PARTICLES The University of Tokyo (JP) 2024-02-21 EP claimed
CN-117178054-A Method for producing virus particles 国立大学法人东京大学 2023-12-05 CN claimed
WO-2022220273-A1 METHOD FOR PRODUCING VIRUS PARTICLES 国立大学法人東京大学 2022-10-20 WO claimed
US-20260144748-A1 POLYOL-BASED MULTI-FUNCTIONAL COMPOUNDS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-28 US disclosed
WO-2026101973-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-15 WO disclosed
US-20260125517-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-07 US disclosed
WO-2026090138-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO disclosed
WO-2026090048-A1 RADIOPAQUE SHAPE MEMORY FOAM DEVICES BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO disclosed
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 US disclosed
US-20260108250-A1 RADIOPAQUE SHAPE MEMORY FOAM DEVICES BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 US disclosed
US-20260108355-A1 DEMINERALIZED BONE FIBER COMPOSITION FOR USE IN MINIMALLY INVASIVE SURGERY ARTERIOCYTE MEDICAL SYSTEMS, INC. (US) 2026-04-23 US disclosed
US-20070041906-A1 Bone substitute composition BONE SUPPORT AB (SE) 2007-02-22 US disclosed
CN-1829543-A A new bone substitute composition BONE SUPPORT AB (SE) 2006-09-06 CN disclosed
EP-1601387-A1 A NEW BONE SUBSTITUTE COMPOSITION Bone Support AB (SE) 2005-12-07 EP disclosed
US-20050119746-A1 Bone mineral substitute BONE SUPPORT AB (SE) 2005-06-02 US disclosed
EP-1465678-A1 A NEW BONE MINERAL SUBSTITUTE Bone Support AB (SE) 2004-10-13 EP disclosed
WO-2004078223-A1 A NEW BONE SUBSTITUTE COMPOSITION BONE SUPPORT AB (SE) 2004-09-16 WO disclosed
WO-2003053488-A1 A NEW BONE MINERAL SUBSTITUTE BONE SUPPORT AB (SE) 2003-07-03 WO disclosed
US-5695742-A MIXTURE OF NONIONIC ORGANIC COMPOUND COMPRISING TRIIODINATED AROMATIC NUCLEUS HAVING AMIDE SUBSTITUENTS AND COMPOUND COMPRISING TWO SUCH TRIIODINATED AROMATIC NUCLEI COVALENTLY BONDED TOGETHER DIBRA S.P.A. (IT) 1997-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL LMNA 2822/4885KDM4E 1347/4885CYP2D6 3233/4885
US-20070041906-A1 Bone substitute composition SOST, BMP2, BMP6 LMNA 4402/4885KDM4E 4621/4885CYP2D6 3991/4885
US-20260108250-A1 RADIOPAQUE SHAPE MEMORY FOAM DEVICES NPPA, CD47, PLAT LMNA 198/4885KDM4E 2425/4885CYP2D6 2498/4885
US-20260108355-A1 DEMINERALIZED BONE FIBER COMPOSITION FOR USE IN MINIMALLY INVASIVE SURGERY BMP2, COL2A1, COL1A1 LMNA 1963/4885KDM4E 3878/4885CYP2D6 1402/4885
US-20260125517-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS MMP1, ILK, MMP13 LMNA 2390/4885KDM4E 992/4885CYP2D6 4224/4885
US-20260144748-A1 POLYOL-BASED MULTI-FUNCTIONAL COMPOUNDS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME CD44, PAM, PLOD3 LMNA 3220/4885KDM4E 2483/4885CYP2D6 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.