Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879010 | 0.89 | KDM4E (0.75) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL1983479 | 0.89 | MAOA (0.81) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL30468736 | 0.89 | MAOA (0.81) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31613986 | 0.89 | RAB9A (0.69) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL1937499 | 0.89 | RAB9A (0.69) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7337235 | 0.81 | MAOA (0.77) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31423805 | 0.81 | MAOA (0.77) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL11618318 | 0.81 | RAB9A (0.85) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL2299504 | 0.80 | MAOA (1.00) | MAOAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL1784468 | 0.80 | KMT2A (0.76) | MAOAKDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | RXFP1, RXFP2, CX3CR1 | MAOA 90/4885KDM4E 4545/4885ALDH1A1 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.