SCHEMBL1784468

SCHEMBL1784468

Nc1ccc2c(=O)c3ccccc3oc2c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.76
MAPT P10636 4/20 0.76
MEN1 O00255 4/20 0.76
KDM4E B2RXH2 4/20 0.76
ALDH1A1 P00352 4/20 0.76
HPGD P15428 4/20 0.76
RAB9A P51151 6/20 0.69
NPC1 O15118 6/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
MAOA P21397 5/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
GLA P06280 2/20 0.67
CASP1 P29466 2/20 0.67
CASP7 P55210 2/20 0.67
HSD17B10 Q99714 2/20 0.67
CYP3A4 P08684 1/20 0.67
PGAM1 P18669 1/20 0.67
ADRB2 P07550 1/20 0.66
GFER P55789 1/20 0.63
TTR P02766 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1937499 0.90 RAB9A (0.69) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL31613986 0.90 RAB9A (0.69) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL21585336 0.89 RAB9A (0.81) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL483639 0.88 MAPT (0.96) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL31261599 0.88 MAPT (0.96) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL11618318 0.87 RAB9A (0.85) KMT2AMAPTMEN1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL11439943 0.86 MAPT (1.00) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL14174147 0.85 MAPT (0.89) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL22301470 0.83 ALDH1A1 (0.79) KMT2AMAPTMEN1KDM4EALDH1A1
Xanthone SCHEMBL41161 0.82 MAOA (1.00) KMT2AMAPTMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5176854-A Xanthone Derivatives HITACHI, LTD. (JP) 1993-01-05 US claimed
US-10400263-B2 Tripeptide rhodamine compound KINGSTON UNIVERSITY HIGHER EDUCATION CORPORATION (GB) 2019-09-03 US disclosed
US-20150240283-A1 Compound Kingston Universty Higher Education Corporation (GB) 2015-08-27 US disclosed
US-20150240283-A1 Compound Kingston Universty Higher Education Corporation (GB) 2015-08-27 US disclosed
CN-102675673-B Ultraviolet ray assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2014-08-13 CN disclosed
CN-102675672-B Ultraviolet aided surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2014-06-18 CN disclosed
CN-102702556-B Ultraviolet-assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2014-03-05 CN disclosed
CN-102643447-B Ultraviolet light assisted surface modification method and product with surface formed by means of method BEIJING WANHEXINYUAN BIOTECHNOLOGIES CO LTD 2013-07-24 CN disclosed
US-8323750-B2 Method of ultraviolet light assisted surface modification and product having a surface formed by this method BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2012-12-04 US disclosed
CN-102702556-A Ultraviolet-assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2012-10-03 CN disclosed
CN-102675673-A Ultraviolet ray assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-102675672-A Ultraviolet aided surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-101372538-B Ultraviolet light assisted surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOTECHNOLOGY CO LTD 2012-08-29 CN disclosed
CN-102643447-A Ultraviolet light assisted surface modification method and product with surface formed by means of method BEIJING WANHEXINYUAN BIOTECHNOLOGIES CO LTD 2012-08-22 CN disclosed
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2011-05-26 US disclosed
CN-101372538-A Ultraviolet light assisted surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOTECHN (CN) 2009-02-25 CN disclosed
EP-0315140-B1 Non-linear optical device HITACHI LTD (JP) 1995-08-23 EP disclosed
US-5176854-A Xanthone Derivatives HITACHI, LTD. (JP) 1993-01-05 US disclosed
EP-0315140-A2 Non-linear optical device HITACHI, LTD. (JP) 1989-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10400263-B2 Tripeptide rhodamine compound RNPEP, PEPD, DNPEP KMT2A 2003/4885MAPT 4315/4885MEN1 3879/4885
US-20150240283-A1 Compound RPIA, STS, CLPP KMT2A 911/4885MAPT 4648/4885MEN1 4222/4885
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD XPA, CYBA, PROC KMT2A 2796/4885MAPT 1624/4885MEN1 3439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.