Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.69 |
| ▸ | PTAFR | P25105 | 1/20 | 0.69 |
| ▸ | HTR1D | P28221 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.52 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127893 | 1.00 | ADRA1D (0.69) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL878627 | 0.87 | SMN1; SMN2 (0.53) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL5720514 | 0.87 | SMN1; SMN2 (0.65) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL30652570 | 0.86 | ADRA1D (0.78) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL15263707 | 0.85 | ADRA1D (0.78) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL8874191 | 0.85 | MAPK1 (0.54) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL19821628 | 0.83 | MAPT (0.71) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL30278565 | 0.83 | MAPT (0.71) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL6619229 | 0.82 | ADRA1D (0.98) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL4804148 | 0.82 | SMN1; SMN2 (0.64) | ADRA1DPTAFRHTR1DHTR2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066834-A2 | Pharmaceutical compositions comprising a phagocyte-modulating agent | Stief, Thomas, Dr. (DE) | 2001-01-10 | — | — | EP | claimed |
| US-4879285-A | PLATELET ACTIVATING FACTOR | ROYAL NORTH SHORE HOSPITAL AND AREA HEALTH SERVICE (AU) | 1989-11-07 | — | — | US | claimed |
| US-4851450-A | GLYCEROLS MONOETHERIFIED WITH VICINAL DIHYDROXYALKYL OR DIACETOXYALKYL | DEMOPOULOS CONSTANTINE A (GR) | 1989-07-25 | — | — | US | claimed |
| US-4595681-A | Administering neutral glycerolipid | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1986-06-17 | — | — | US | claimed |
| US-12011465-B1 | Method of lubricating bodily tissue using an amnion derived therapeutic composition | AMNIO TECH LLC (US) | 2024-06-18 | — | — | US | disclosed |
| WO-2024108091-A1 | PLATELET-BINDING PROTEINS AND CONJUGATES THEREOF, PARTICLES COMPRISING THEM AND USES THEREOF | HAIMA THERAPEUTICS, LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024108094-A1 | LYOPHILIZATION BUFFERS FOR PEPTIDE-DECORATED LIPOSOMES | HAIMA THERAPEUTICS, LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20240108748-A1 | COMPOSITIONS AND METHODS FOR TARGETED AMPLIFICATION OF COAGULATION AND PHAGOCYTOSIS | CASE WESTERN RESERVE UNIVERSITY | 2024-04-04 | — | — | US | disclosed |
| US-20240024430-A1 | SYNTHETIC PLATELETS | UNIV CASE WESTERN RESERVE (US) | 2024-01-25 | — | — | US | disclosed |
| EP-4291247-A1 | COMPOSITIONS AND METHODS FOR TARGETED AMPLIFICATION OF COAGULATION AND PHAGOCYTOSIS | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-12-20 | — | — | EP | disclosed |
| US-20230390385-A1 | Compositions and Methods for Prevention and Treatment of Immune Complex Disease | COWAN FRED M (US) | 2023-12-07 | — | — | US | disclosed |
| US-20230270412-A1 | METHODS AND DEVICES FOR PREPARATION OF ULTRASOUND CONTRAST AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2023-08-31 | — | — | US | disclosed |
| EP-0163317-B1 | QUINONE DERIVATIVES, METHOD AND USE OF PREPARING SAME, AND PHARMACEUTICAL COMPOSITION | Eisai Co., Ltd. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4762829-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| US-4742058-A | AMIDES, ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| US-4725588-A | Alkyl phospholipid antihypertensive agents in method of lowering blood pressure | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1988-02-16 | — | — | US | disclosed |
| US-4725588-A | Alkyl phospholipid antihypertensive agents in method of lowering blood pressure | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1988-02-16 | — | — | US | disclosed |
| EP-0187989-A1 | Bis-imidazolinoamino derivatives as useful antiallergy compounds | USV PHARMACEUTICAL CORPORATION (US) | 1986-07-23 | — | — | EP | disclosed |
| US-4595681-A | Administering neutral glycerolipid | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0110397-A2 | Polyprenyl compound and drug containing the same | Eisai Co., Ltd. (JP) | 1984-06-13 | — | — | EP | disclosed |