Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878627 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL5720514 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL31577380 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL8874191 | 0.83 | MAPK1 (0.54) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL243890 | 0.82 | ADRA1D (0.69) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL1127893 | 0.82 | ADRA1D (0.69) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL1856364 | 0.82 | LMNA (0.51) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL2522867 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL170993 | 0.80 | LMNA (0.56) | SMN1; SMN2MEN1KMT2AAKT1LMNA | |
| SCHEMBL11135866 | 0.79 | AKT1 (0.73) | SMN1; SMN2MEN1KMT2AAKT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076377-A2 | GENES ENCODING A NOVEL TYPE OF LYSOPHOPHATIDYLCHOLINE ACYLTRANSFERASES AND THEIR USE TO INCREASE TRIACYLGLYCEROL PRODUCTION AND/OR MODIFY FATTY ACID COMPOSITION | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-06-26 | — | — | WO | disclosed |