SCHEMBL1127893

SCHEMBL1127893

C=CCOC[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(C)=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 1/20 0.69
PTAFR P25105 1/20 0.69
HTR1D P28221 1/20 0.69
HTR2C P28335 1/20 0.69
ADRA1B P35368 1/20 0.69
DRD3 P35462 1/20 0.69
TMEM97 Q5BJF2 1/20 0.69
MAPT P10636 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.52
NR5A2 O00482 1/20 0.52
NR5A1 Q13285 1/20 0.52
RECQL P46063 1/20 0.51
ALDH1A1 P00352 2/20 0.50
PRKD3 O94806 1/20 0.50
PRKCG P05129 1/20 0.50
PRKCB P05771 1/20 0.50
PRKCA P17252 1/20 0.50
PRKCH P24723 1/20 0.50
AKT1 P31749 1/20 0.50
PRKCI P41743 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243890 1.00 ADRA1D (0.69) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL878627 0.87 SMN1; SMN2 (0.53) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL5720514 0.87 SMN1; SMN2 (0.65) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL30652570 0.86 ADRA1D (0.78) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL15263707 0.85 ADRA1D (0.78) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL8874191 0.85 MAPK1 (0.54) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL19821628 0.83 MAPT (0.71) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL30278565 0.83 MAPT (0.71) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL6619229 0.82 ADRA1D (0.98) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL4804148 0.82 SMN1; SMN2 (0.64) ADRA1DPTAFRHTR1DHTR2CADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2229157-A1 COMPRESSED CHEWING GUM TABLET Fertin Pharma A/S (DK) 2010-09-22 EP claimed
EP-2229156-A1 CHEWING GUM TABLET AND METHOD OF DOSING PHARMACEUTICALLY ACTIVE INGREDIENTS IN SUCH CHEWING GUM TABLET Fertin Pharma A/S (DK) 2010-09-22 EP claimed
EP-2229158-A1 COMPRESSED CHEWING GUM TABLET Fertin Pharma A/S (DK) 2010-09-22 EP claimed
WO-2009080022-A1 COMPRESSED CHEWING GUM TABLET FERTIN PHARMA A/S (DK) 2009-07-02 WO claimed
WO-2009080020-A1 CHEWING GUM TABLET AND METHOD OF DOSING PHARMACEUTICALLY ACTIVE INGREDIENTS IN SUCH CHEWING GUM TABLET FERTIN PHARMA A/S (DK) 2009-07-02 WO claimed
WO-2009080021-A1 COMPRESSED CHEWING GUM TABLET FERTIN PHARMA A/S (DK) 2009-07-02 WO claimed
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS NASTECH PHARMACEUTICAL COMPANY INC. 2007-04-05 US claimed
US-20240238240-A1 Cannabinoid Pouch NORDICCAN A/S (DK) 2024-07-18 US disclosed
US-11963944-B2 Cannabinoid pouch NORDICCAN A/S (DK) 2024-04-23 US disclosed
WO-2024077085-A1 TARGETING PHOSPHOLIPASE A2 (PLA2) IN CANCER MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-04-11 WO disclosed
US-11911375-B2 Solid oral nicotine formulation FERTIN PHARMA A/S (DK) 2024-02-27 US disclosed
US-11534421-B2 Cannabinoid pouch NORDICCAN A/S 2022-12-27 US disclosed
EP-4000424-B1 NICOTINE POUCH COMPOSITION PHILIP MORRIS PRODUCTS SA (CH) 2022-11-09 EP disclosed
EP-0948605-A1 TRUNCATED PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE ICOS CORPORATION (US) 1999-10-13 EP disclosed
EP-0523189-B1 CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES VICAL INC (US) 1999-06-16 EP disclosed
WO-1999009147-A1 TRUNCATED PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE ICOS CORPORATION (US) 1999-02-25 WO disclosed
WO-1997040838-A1 NEW USE SCOTIA LIPIDTEKNIK AB (SE) 1997-11-06 WO disclosed
WO-1997031660-A1 CONTACT LENS TREATING COMPOSITIONS, METHODS OF TREATMENT, AND NOVEL LENSES VISION PHARMACEUTICALS L.P. (US) 1997-09-04 WO disclosed
EP-0673426-A1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE ICOS CORPORATION (US) 1995-09-27 EP disclosed
WO-1995009921-A1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE ICOS CORPORATION (US) 1995-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS PGF, PLAT, PTAFR ADRA1D 1551/4885PTAFR 3/4885HTR1D 3160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.