Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439441 | 0.85 | KDM4E (0.50) | NPSR1MTNR1AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL2438493 | 0.84 | TAAR1 (0.40) | NPSR1MTNR1AADRB2ADRB1KDM4E | |
| SCHEMBL12895268 | 0.77 | GRIN2B (0.46) | MTNR1A | |
| SCHEMBL25299494 | 0.75 | PPARA (0.49) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL2437293 | 0.75 | TAAR1 (0.59) | MTNR1AMTNR1BTAAR1 | |
| SCHEMBL31689751 | 0.75 | TAAR1 (0.59) | MTNR1AMTNR1BTAAR1 | |
| SCHEMBL4685285 | 0.73 | L3MBTL1 (0.54) | NPSR1MTNR1AKDM4EALDH1A1THRB | |
| SCHEMBL2441990 | 0.71 | PTPN1 (0.35) | ALDH1A1 | |
| SCHEMBL28892660 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL1470891 | 0.71 | IRAK4 (0.54) | NPSR1MTNR1AADRB2ADRB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |