Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441993 | 0.82 | MAPT (0.40) | RAB9AKMT2ASMN1; SMN2PPARGPPARA | |
| SCHEMBL2441994 | 0.78 | NPC1 (0.39) | RAB9ASMN1; SMN2ELANENPC1 | |
| SCHEMBL2472594 | 0.73 | PPARG (0.60) | KMT2APPARGPPARAPPARDMAPT | |
| SCHEMBL29025518 | 0.72 | MEN1 (0.45) | KMT2AMAPT | |
| SCHEMBL6543501 | 0.72 | ADRB3 (0.39) | PPARGPPARAPPARDP2RY14MAPT | |
| SCHEMBL2439261 | 0.71 | NPSR1 (0.39) | ALDH1A1 | |
| SCHEMBL2438493 | 0.71 | TAAR1 (0.40) | ALDH1A1 | |
| SCHEMBL2440537 | 0.71 | PPARG (0.45) | RAB9ASMN1; SMN2PPARGPPARAPPARD | |
| SCHEMBL6543074 | 0.70 | PPARG (0.39) | PPARGPPARAPPARDALDH1A1 | |
| SCHEMBL5703664 | 0.70 | KMT2A (0.39) | PTPN1RAB9AKMT2ASMN1; SMN2PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |