Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.43 |
| ▸ | KIT | P10721 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24393095 | 0.82 | HRH4 (0.38) | PDE2A | |
| SCHEMBL24392257 | 0.81 | PDE2A (0.39) | PDE2AKITKDM4EALDH1A1GAA | |
| SCHEMBL24393353 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1GAAEGLN2HPGD | |
| SCHEMBL24392490 | 0.72 | KDM4E (0.48) | PDE2AKDM4EALDH1A1GAAEGLN2 | |
| SCHEMBL24392296 | 0.71 | PDE2A (0.37) | PDE2AKITKDM4EALDH1A1GAA | |
| SCHEMBL24391742 | 0.68 | KDM4E (0.44) | PDE2AKDM4EALDH1A1GAAEGLN2 | |
| SCHEMBL786000 | 0.67 | HTR3E (0.54) | ALDH1A1GAASMN1; SMN2LMNANPC1 | |
| SCHEMBL24392146 | 0.67 | OPRK1 (0.36) | PAK1 | |
| SCHEMBL24392676 | 0.63 | CSNK2A2 (0.34) | PDE2AKITPDE10A | |
| SCHEMBL24392682 | 0.62 | OPRK1 (0.34) | PDE2AKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091048-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |