Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24393093 | 0.82 | PDE2A (0.43) | PDE2A | |
| SCHEMBL24391973 | 0.77 | ENPP1 (0.34) | PDE2AOPRK1ENPP1 | |
| SCHEMBL24392395 | 0.73 | ENPP1 (0.33) | PDE2AENPP1 | |
| SCHEMBL24392146 | 0.71 | OPRK1 (0.36) | OPRK1 | |
| SCHEMBL24393360 | 0.71 | ALDH1A1 (0.34) | ENPP1 | |
| SCHEMBL24392555 | 0.68 | ENPP1 (0.36) | PDE2AENPP1 | |
| SCHEMBL24392676 | 0.68 | CSNK2A2 (0.34) | HRH4PDE2AOPRK1 | |
| SCHEMBL24392682 | 0.67 | OPRK1 (0.34) | PDE2AOPRK1 | |
| SCHEMBL9967041 | 0.63 | AKT1 (0.68) | STK4STK3LRRK2 | |
| Ammonia Solution, Strong SCHEMBL27902618 | 0.63 | CHRNB2 (0.47) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091048-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |