Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24392490 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1GAAEGLN2HPGD | |
| SCHEMBL24391742 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1GAAEGLN2HPGD | |
| SCHEMBL24393093 | 0.76 | PDE2A (0.43) | KDM4EALDH1A1GAAEGLN2HPGD | |
| SCHEMBL24393360 | 0.75 | ALDH1A1 (0.34) | KDM4EALDH1A1GAAEGLN2HPGD | |
| SCHEMBL5447355 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1GAAEGLN2HPGD | |
| SCHEMBL24393051 | 0.69 | ALDH1A1 (0.46) | KDM4EALDH1A1EGLN2HPGDSMN1; SMN2 | |
| SCHEMBL15696254 | 0.67 | PTGS2 (0.50) | KDM4EGAAHPGDSMN1; SMN2MAPT | |
| SCHEMBL24393158 | 0.66 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL24393212 | 0.66 | ALDH1A1 (0.35) | KDM4EALDH1A1EGLN2MAPTKMT2A | |
| SCHEMBL24393049 | 0.66 | ALDH1A1 (0.35) | KDM4EALDH1A1EGLN2MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091048-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |