Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 12/20 | 0.50 |
| ▸ | AKT2 | P31751 | 12/20 | 0.50 |
| ▸ | AKT3 | Q9Y243 | 6/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439564 | 0.86 | AKT1 (0.49) | AKT1AKT2AKT3OPRM1OPRK1 | |
| SCHEMBL2435312 | 0.79 | AKT1 (0.79) | AKT1AKT2AKT3 | |
| SCHEMBL3979847 | 0.79 | AKT1 (0.79) | AKT1AKT2AKT3 | |
| SCHEMBL5480762 | 0.77 | AKT1 (0.43) | AKT1AKT2AKT3OPRM1OPRK1 | |
| SCHEMBL5261966 | 0.73 | ALDH1A1 (0.59) | AKT1AKT2AKT3 | |
| SCHEMBL5260840 | 0.73 | AKT1 (0.68) | AKT1AKT2AKT3DRD2DRD4 | |
| SCHEMBL5257804 | 0.69 | AKT1 (0.56) | AKT1AKT2AKT3DRD2DRD4 | |
| SCHEMBL7063258 | 0.67 | CCR8 (0.52) | OPRM1OPRK1OPRL1 | |
| SCHEMBL2441673 | 0.65 | AKT1 (0.78) | AKT1AKT2AKT3 | |
| SCHEMBL2437301 | 0.65 | AKT1 (0.78) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362909-A2 | MAMMALIAN GENES INVOLVED IN INFECTION | Zirus, Inc. (US) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010039778-A2 | MAMMALIAN GENES INVOLVED IN INFECTION | Zirus, Inc. (US) | 2010-04-08 | — | — | WO | disclosed |