Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15243730 | 0.76 | MBTD1 (0.62) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6501384 | 0.73 | ALDH1A1 (0.66) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL9033977 | 0.73 | DRD2 (0.59) | KDM4EALDH1A1OPRM1LMNA | |
| SCHEMBL25967968 | 0.73 | ALDH1A1 (0.65) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6528757 | 0.72 | KDM4E (0.64) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6496007 | 0.72 | OPRM1 (0.83) | OPRM1OPRK1OPRL1 | |
| SCHEMBL6501376 | 0.71 | CCR8 (0.52) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6499571 | 0.71 | ALDH1A1 (0.75) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL5545954 | 0.71 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2 | |
| SCHEMBL7174115 | 0.71 | FAAH (0.62) | CCR8KDM4EALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |