Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397600 | 0.82 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTTDP1APEX1 | |
| SCHEMBL26271460 | 0.80 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL14841474 | 0.77 | HSD11B1 (0.35) | ALDH1A1POLBMAPTTDP1RECQL | |
| SCHEMBL24411659 | 0.76 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL18706310 | 0.74 | THRB (0.38) | ALDH1A1POLBMAPTTDP1APEX1 | |
| SCHEMBL24397537 | 0.74 | EPHX2 (0.35) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL8164815 | 0.74 | BRD4 (0.38) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL24411661 | 0.73 | POLB (0.33) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL24411634 | 0.72 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL17294238 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022094148-A1 | CONJUGATION REAGENTS AND METHODS USING 1,2-CYCLOHEXANEDIONES | Encodia, Inc. (US) | 2022-05-05 | — | — | WO | disclosed |