Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24411659 | 0.81 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL24411661 | 0.79 | POLB (0.33) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL24397600 | 0.73 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL24397537 | 0.73 | EPHX2 (0.35) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL24397614 | 0.72 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL8164815 | 0.67 | BRD4 (0.38) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL13946994 | 0.67 | NOS3 (0.42) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL24397610 | 0.66 | ENO1 (0.35) | — | |
| SCHEMBL5157177 | 0.61 | CYP1A2 (0.49) | ALDH1A1MAPTTDP1 | |
| SCHEMBL52516 | 0.59 | BRD4 (0.51) | ALDH1A1POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639366-B2 | Conjugation reagents and methods using 1,2-cyclohexanediones | Encodia, Inc. (US) | 2023-05-02 | — | — | US | disclosed |
| US-20220144885-A1 | CONJUGATION REAGENTS AND METHODS USING 1,2-CYCLOHEXANEDIONES | Encodia, Inc. (US) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144885-A1 | CONJUGATION REAGENTS AND METHODS USING 1,2-CYCLOHEXANEDIONES | TNNI3, CHD1, TNNT2 | ALDH1A1 1150/4885POLB 2499/4885MAPT 4752/4885 |
| US-11639366-B2 | Conjugation reagents and methods using 1,2-cyclohexanediones | TNNI3, CHD1, TNNT2 | ALDH1A1 1150/4885POLB 2499/4885MAPT 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.