SCHEMBL24399507

SCHEMBL24399507

Brc1ccc2c3c(ccc2c1)O/C=C\CCOc1ccc2cc(Br)ccc2c1-3

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
BLM P54132 1/20 0.41
SIRT2 Q8IXJ6 7/20 0.33
SIRT1 Q96EB6 1/20 0.33
DPP4 P27487 2/20 0.32
KMT2A Q03164 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
ERN1 O75460 1/20 0.31
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
PIK3CG P48736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3568497 0.83 MAPT (0.52) LMNAMAPTHTTBLMSIRT2
SCHEMBL3568948 0.81 MAPT (0.44) LMNAMAPTHTTBLMSIRT2
SCHEMBL3565631 0.81 MAPT (0.44) LMNAMAPTHTTBLMSIRT2
SCHEMBL3561759 0.77 SIRT2 (0.40) LMNAMAPTHTTBLMSIRT2
SCHEMBL13568115 0.75 LMNA (0.44) LMNAMAPTHTTBLMSIRT2
SCHEMBL13568204 0.73 MAPT (0.38) LMNAMAPTHTTBLMSIRT2
SCHEMBL14548104 0.73 MAPT (0.38) LMNAMAPTHTTBLMSIRT2
SCHEMBL14870330 0.71 CYP2A6 (0.44) MAPTSIRT2SIRT1DPP4KMT2A
SCHEMBL4024270 0.68 MAPT (0.44) LMNAMAPTHTTBLMSIRT2
SCHEMBL4031496 0.66 MAPT (0.42) LMNAMAPTHTTBLMSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022090523-A1 CHIRAL POLYMERS AND USE THEREOF CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2022-05-05 WO disclosed