Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.36 |
| ▸ | YTHDF3 | Q7Z739 | 2/20 | 0.36 |
| ▸ | YTHDF1 | Q9BYJ9 | 2/20 | 0.36 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30401336 | 0.84 | CSNK2A2 (0.41) | CSNK2A2CSNK2BTAAR1KDRFLT1 | |
| SCHEMBL25374531 | 0.84 | CSNK2A2 (0.41) | CSNK2A2CSNK2BTAAR1KDRFLT1 | |
| SCHEMBL30402574 | 0.79 | CSNK2A2 (0.40) | CSNK2A2CSNK2BLMNAKDM4EHPGD | |
| SCHEMBL25376248 | 0.79 | CSNK2A2 (0.40) | CSNK2A2CSNK2BLMNAKDM4EHPGD | |
| SCHEMBL24399669 | 0.74 | BRAF (0.71) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL30402640 | 0.67 | FLT1 (0.38) | KDRFLT1LMNAGAA | |
| SCHEMBL24399590 | 0.67 | FLT1 (0.38) | KDRFLT1LMNAGAA | |
| SCHEMBL24399619 | 0.66 | KDR (0.46) | KDRFLT1BRAFLCKTEK | |
| SCHEMBL24399633 | 0.66 | ROCK1 (0.45) | TAAR1 | |
| SCHEMBL30402694 | 0.66 | ROCK1 (0.45) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |