Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.36 |
| ▸ | LOX | P28300 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373280 | 0.83 | ST14 (0.52) | MAOBLOXL2LOX | |
| SCHEMBL24400400 | 0.82 | LOXL2 (0.40) | THRBMAPK1MAOBLIPELOXL2 | |
| Hydrochloric Acid SCHEMBL1713787 | 0.81 | MAOB (0.50) | MAOBLOXL2LOX | |
| SCHEMBL24401106 | 0.78 | HPGD (0.51) | THRBMAPK1MAOBPOLBL3MBTL1 | |
| SCHEMBL8310340 | 0.77 | ALDH1A1 (0.64) | THRBMAPK1MAOBALDH1A1POLB | |
| SCHEMBL24400591 | 0.77 | L3MBTL1 (0.45) | THRBMAPK1MAOBALDH1A1POLB | |
| SCHEMBL4380974 | 0.76 | MEN1 (0.63) | MAOBALDH1A1L3MBTL1LOXL2KDM4E | |
| SCHEMBL30744447 | 0.76 | MEN1 (0.63) | MAOBALDH1A1L3MBTL1LOXL2KDM4E | |
| SCHEMBL5659053 | 0.76 | LOXL2 (0.44) | MAOBLOXL2LOX | |
| SCHEMBL3890599 | 0.76 | L3MBTL1 (0.53) | MAPK1MAOBALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238974-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089454-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |