Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924211 | 0.91 | MAPT (0.36) | ALDH1A1MAPTPKMKDM4ENPC1 | |
| SCHEMBL24401144 | 0.91 | MAPT (0.36) | ALDH1A1MAPTPKMKDM4ENPC1 | |
| SCHEMBL6306238 | 0.88 | MAPT (0.38) | ALDH1A1MAPTPKMKDM4ENPC1 | |
| SCHEMBL25712948 | 0.84 | KDM4E (0.38) | ALDH1A1MAPTPKMKDM4ENPC1 | |
| SCHEMBL25712865 | 0.81 | CYP1A2 (0.39) | ALDH1A1KDM4ENPC1TSHR | |
| SCHEMBL25120298 | 0.80 | CSNK2A2 (0.36) | ALDH1A1MAPTKDM4ENPC1HSD17B10 | |
| SCHEMBL25978729 | 0.77 | TSHR (0.41) | ALDH1A1MAPTPKMKDM4ENPC1 | |
| SCHEMBL25712964 | 0.75 | SUV39H2 (0.34) | ALDH1A1MAPTPKMKDM4EGAA | |
| SCHEMBL25119888 | 0.74 | CCNT1 (0.31) | — | |
| SCHEMBL24400818 | 0.74 | ADORA1 (0.38) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234968-A1 | METHYL-SUBSTITUTED BENZOBISOXAZOLE COMPOUND AND USE THEREOF | TONGHUA DONGBAO PHARMACEUTICAL CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | GLP1R, GIPR, GPR119 | ALDH1A1 1731/4885MAPT 4433/4885PKM 3202/4885 |
| US-20230234968-A1 | METHYL-SUBSTITUTED BENZOBISOXAZOLE COMPOUND AND USE THEREOF | CYP11B2, CYP11B1, TPMT | ALDH1A1 1062/4885MAPT 2181/4885PKM 594/4885 |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | GLP1R, GIPR, GPR119 | ALDH1A1 1731/4885MAPT 4433/4885PKM 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.